How Vitamin K2 and D3 May Work Together to Reduce Blood Pressure

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Is vitamin K2 and D3 beneficial for high blood pressure?

Vitamin K and vitamin D has positive effects on blood pressure. We have seen this in many studies. However, current research shows a link between the two vitamins that can act together to increase blood pressure. So, supplementation can be an excellent way to reduce your blood pressure. 

Let’s take a closer look at the study.

Low Levels of Vitamin K and D Associated with High Blood Pressure

Lack of vitamin K and D has long been associated with an increased risk of heart problems. However, a recent study by researchers at the EMGO Institute for Health and Care Research shows new findings.

For the first time, scientists are able to draw a link between the two vitamins and how they influence blood pressure. The researchers found low vitamin K and D levels to cause:

  • 4.8 mmHg increase in systolic blood pressure
  • 3.1 mmHg increase in diastolic blood pressure

Not only that, but scientists also found a lack of the two vitamins to increase the risk of hypertension by 62%.

The study focused on 402 participants and collected data for more than 6-years. The findings can be easily generalized as the researchers saw the highest blood pressure in people with the lowest levels of vitamin D and K. 

Individual Studies with Vitamin K and D

Studies with each of the vitamin also show effects on blood pressure. In a study published in the Journal of the American Heart Association, vitamin K2 reduced blood pressure and arterial stiffness. So, the link between vitamin K2 and blood pressure is proven.

Coming to vitamin D3, it also has beneficial results on blood pressure. In one study, vitamin D3 supplementation resulted in a decrease in systolic blood pressure. The scientists found the blood pressure to decrease more as levels of vitamin D went up.

In this case, too, vitamin D3 is linked with blood pressure. So, it’s clear the two vitamins do play a role in keeping your blood pressure normal. Now, let’s see how the two vitamins might bring down your blood pressure. 

How Vitamin K2 and D3 May Reduce Blood Pressure

Vitamin K2 is crucial to heart health. It stimulates a protein that stops calcium from being deposited around the linings of the blood vessels. This might help prevent the constriction of blood vessels that make them narrow and lead to high blood pressure. 

In studies, vitamin K2 supplementation led to-

  • 52% drop in chances of developing artery calcification
  • 57% less risk of dying from cardiovascular diseases

Scientists now know that you can experience a 9% reduction in heart diseases by consuming 10 mcg of K2 per day.

Researchers are still studying how exactly vitamin K2 helps in reducing blood pressure. Interestingly, vitamin K1 doesn’t have the same effects on blood pressure or heart diseases. 

 Now let’s take up vitamin D3. In some studies, increasing the levels of D3 in the body resulted in reduced blood pressure. Some studies also linked vitamin D deficiency with high blood pressure

However, a number of studies have also not found any relation between the two.

Researchers agree we need more research to say anything for sure. Scientists believe there can be a number of reasons for studies not to find any relationship between D3 and blood pressure. But one thing is sure- we do have a number of biological mechanisms by which vitamin D3 affects blood pressure. 

Additionally, you need both the vitamins for calcium to do its job. Vitamin D3 ensures you can absorb calcium in your bloodstream, while K2 delivers calcium to the right places. Also, both vitamins work together to help us stay healthy.

Vitamin K2 and D3

We will now share a few words on both the vitamins. Vitamin K2 is a form of vitamin K found in animal meat, eggs, and dairy products. K2 is also the longest-lasting and most bioactive form of vitamin K. As a result, you can get more benefits from K2 when it comes to heart health. 

Vitamin K deficiency is also common in children. It can also happen in the newborn due to various reasons. However, deficiency is rare in adults. Children need a good dose of vitamin K at birth to prevent many adverse medical conditions.

Vitamin D is the sunshine vitamin. Our skin can make vitamin D3 from sunlight. It’s also present in meat, dairy, eggs, and fishes. Vitamin D3 is more effective in increasing blood levels of vitamin D compared to other forms. Many people in many countries have a deficiency of vitamin D due to less exposure to sunlight.

We need both the vitamins to stay and function normally. As a result, you should ensure you are not suffering from a deficiency of the vitamins. You can try our recommended multivitamins to get your daily dose of vitamins crucial for the body.

People who have a varied diet should easily meet requirements of both vitamins. You should get tested if you think you are deficient in either vitamin K or vitamin D. It’s not good to start supplementing without professional advice.

Final Thoughts

Lack of vitamin K2 and D3 has a negative effect on blood pressure. You will certainly experience a spike in your blood pressure if you are deficient in the two vitamins.

However, scientists are not sure how the two-act together to maintain healthy blood pressures. We have discussed the probable causes above, so you can form an informed idea. We will update this article as new research comes out to help you learn the latest.  We suggest you consult a physician before supplementing with any vitamin for medical reasons. Your condition might be due to underlying causes unknown to you. Otherwise, you can try vitamins for overall health benefits.


What is vitamin K2 and D3 good for?

Vitamin K2 and D3, when taken together, is good to lower blood pressure. The combination reduces hypertension and reduces the risks of many cardiovascular diseases. Plus, both the vitamins help us absorb and make use of calcium to develop strong bones. Additionally, both vitamins have individual benefits.

Should you take vitamin K2 and vitamin D3 at the same time?

You can take vitamin K2 and D3 together for reducing bone loss. The two vitamins together can also help lower blood pressure and prevent cardiovascular ailments. Otherwise, you don’t need to take the two vitamins together unless prescribed by your doctor. 

How much vitamin K2 and vD3 should you take?

You can take 400 – 800UI of vitamin D3 and 90 – 360ug of vitamin K2. Researchers have used similar dosages in studies for bone loss and heart health. Consult your physician for a recommended dose. 

Can vitamin D3 and K2 help in weight loss?

Vitamin D3 and K2 may not be ideal for losing weight. We don’t yet have any studies evaluating the effect of the two vitamins on weight loss. However, healthy levels of vitamin D3 may support weight loss efforts. But you can’t hope to lose weight just by taking the two vitamins together. 

What are the side effects of vitamin D3 and K2?

Vitamin D3 and K2 can cause side effects like vomiting or stomach upset. Some people may also experience nausea or constipation. Not all people encounter the same or all side effects.

Why is vitamin D3 taken with K2?

The combination of vitamin D3 and K2 can be beneficial for a few specific cases. Examples include increasing bone mineral density and promoting heart health. Everyone doesn’t need to take the combination unless your doctor says so.

Where can I find the best vitamin D3 and K2 supplements reviews?

You can check out the customer reviews on vitamin D and K2 supplements in online stores. Keep an eye for fake reviews to promote the product. Compare reviews of multiple stores to determine the quality of your supplement.

Is too much vitamin K2 unsafe?

Vitamin K2 is safe when you take the recommended dose. However, too much vitamin K2 may give you diarrhea. So, it’s always better to stick to safe dosages.

Should I take vitamin D in the morning or night?

You can take vitamin D in the morning or night, as you please. No studies exist to assess the best time of taking vitamin D. You can take your vitamin D with meals for better absorption.

Is vitamin D3 better than D2?

Vitamin D3 may be more efficient in increasing your vitamin D levels compared to just vitamin D. It’s also the form naturally present in foods. So, it may be a good idea to take D3.